Clinical Prognosis of AKT2 and COX2 Mutation on Colorectal Cancer
Author(s):
Caroline Tatim Saad, Maria Cristina Sartor, Camila Cavalcanti Barcelos Rodrigues, Alexandre Bueno Merlini*, M�¡rio Rodrigues Montemor Netto and Jorge Eduardo Fouto Matias
Cancer has become one of the most mortal diseases in the world. It was estimated in 2018 18.1 millions new cancer cases. The colorectal cancer (CRC) is the third most common type of cancer in men and the second in women around the world [1]. The incidence risk in the occidental population is 5% to 6%, and it can increase to 15% to 30% when a first degree relative has the diagnoses. In hereditary predisposition cancer syndrome like the Lynch syndrome it can grow up to 80% [2].