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Medical & Clinical Research

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Intensity Modulated Radiotherapy For Recurrent Spine Aneurysmal Bone Cyst In Adolescence-Case Report And Review of Literature


Author(s): L. Marinova, V. Vasileva, I. Gabrovski, N. Kahchiev, R. Radev

Aneurysmal bone cysts are rarely diagnosed aggressive benign bone tumors that require CT and MRI imaging and strict histopathological analysis. This clinically and histologically benign tumor is mainly diagnosed in children and adolescents in the long bones of the limbs, but in 12%-30% it is localized in the spine.

Since the value of external beam radiotherapy (EBRT) for aneurysmal bone cyst (ABC) has not been well defined, we present our observations and treatment outcome after the realization of intensity modulated radiotherapy (IMRT) up to total dose 30 Gy for recurrent spine aneurysmal bone cyst in adolescent age. In this article, for the first time in the world medical literature, an MRI imaging finding after performed IMRT in recurrent ABC is presented.

Our observations lead to the conclusion, that radiation therapy is an effective treatment method for relapsed or inoperable disease, achieving not only a symptomatic pain-relieving effect, but also a significant tumor reduction and restoration of the bone structure