Medical & Clinical Research

Author(s): Say-yed Hesameddin Tafreshi*

Background: To control the COVID-19 pandemic, governments implemented both pharmacological and non-pharmacological interventions. However, the answers to questions, “How effective are these interventions?” and “Can the pandemic be controlled only by implementation of an intervention?” are very important for decision makers in public health policy. Methods: To evaluate efficacy of the most important pharmacological and non-pharmacological interventions of the COVID-19 pandemic control, a literature search was conducted from 2019 to January 2022 in the Google Scholar and PubMed databases using appropriate keywords. Results: The results of the literature review in efficacy analysis have indicated that many factors and variables influence on the efficacy and effectiveness of the interventions and each intervention alone is insufficient to control of the pandemic and overemphasizing on specific intervention such as vaccination, is misleading and may propagate the disease. Conclusions: Pharmacological and non-pharmacological interventions have no superiority over each other and a logical and feasible combination and implementation of these interventions are required for effective