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Medical & Clinical Research

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Rare Evolution of an Epstein-Barr-virus-Positive Atypical B-Lymphoproliferative disorder Into Classic Hodgkin Lymphoma


Author(s): Daniel Benharroch

A 78 years-old woman exhibited a group of axillary lymph nodes, the largest reaching 2 cm in diameter. The histopathology was consistent, a priori with advanced-age related, Epstein-Barr virus-positive, atypical B-cell lymphoproliferative disorder. A revision with additional immunostaining seems to favor a progression into classic Hodgkin lymphoma. A proposed conversion may account for such clinical features as the deterioration in the patient’s condition. It might indicate, moreover, the mitigation for an early misdiagnosis