Stem Cell therapy for Hair Loss
Author(s):
M S Al Abadie, N Abed and M Mahfoudh
Stem cell research has made significant strides since its inception, with applications expanding into regenerative medicine and therapeutic treatments for various conditions, including hair loss. The discovery of hematopoietic stem cells (HSCs) in the 1960s and the advent of induced pluripotent stem cells (iPSCs) in 2006 have propelled the field into new frontiers. Stem cell-based therapies for hair loss focus on regenerating hair follicles, with sources ranging from adipose-derived stem cells (ADSCs) to hair follicle mesenchymal stem cells. These approaches leverage the unique properties of stem cells, including self-renewal and differentiation, to address androgenetic alopecia and other conditions. Stem cells promote hair growth by activating dermal papilla cells, stimulating follicular regeneration, and enhancing hair density. Techniques such as intradermal injections combined with growth factors and vitamins further optimize therapeutic outcomes. This review highlights the mechanisms, sources, and applications of stem cells in hair loss treatment, emphasizing their potential to revolutionize hair restoration therapies.